한양대학교 ERICA 산학협력단

- 연구자검색

- 우수연구성과

- 금주의 우수논문

- HIGHLY CITED PAPERS (HCP)

- ERICA 연구산학뉴스

> 연구정보 > 연구성과 > HIGHLY CITED PAPERS (HCP)

전임교원이 최근 5년간 출판한 논문 중, 연도별 카테고리별 피인용 상위 1%에 달성된 논문
매월 1회 업데이트

게시글
SCIE Article [Excluded] Engineering of cell microenvironment-responsive polypeptide nanovehicle co-encapsulating a synergistic combination of small molecules for effective chemotherapy in solid tumors
Author	Ramasamy, Thiruganesh; Ruttala, Hima Bindu; Chitrapriya, Nataraj; Poudal, Bijay Kumar; Choi, Ju Yeon; Kim, Ssang Tae; Youn, Yu Seok; Ku, Sae Kwang; Choi, Han-Gon; Yong, Chul Soon
Corresponding Author Info	Prof. Choi, Han-Gon (최한곤 교수, 약학과)
Professor
E-mail	hangon@hanyang.ac.kr
Document Type
Source	ACTA BIOMATERIALIA 2017, 48, 131-143
Times Cited	Excluded
External Information	http://www.sciencedirect.com/science/article/pii/S1742706116305621
Abstract	- 출판연도: JAN 15 2017 [History] - 2018년 8월 13일 현재 HCP 리스트에서 제외되어 있습니다. - 7월/8월 2017년 부로, 이 인용 빈도가 높은 논문의 인용 횟수가 분야와 출판 연도에 대해 Materials Science 관련 학술 분야에서 상위 1%에 올랐습니다. [Abstract] In this study, we report a facile method to construct a bioactive (poly(phenylalanine)-b-poly(t-histidine)-b-poly(ethylene glycol) polypeptide nanoconstruct to co-load doxorubicin (DOX) and quercetin (QUR) (DQ-NV). The smart pH-sensitive nanovehicle was fabricated with precisely tailored drug-to-carrier ratio that resulted in accelerated, sequential drug release. As a result of ratiometric loading, QUR could significantly enhance the cytotoxic potential of DOX, induced marked cell apoptosis; change cell cycle patterns, inhibit the migratory capacity of sensitive and resistant cancer cells. In particular, pro-oxidant QUR from DQ-NV remarkably reduced the GSH/GSSG ratio, indicating high oxidative stress and damage to cellular components. DQ-NV induced tumor shrinkage more effectively than the single drugs in mice carrying subcutaneous SCC-7 xenografts. DQ-NV consistently induced high &#101xpression of caspase-3 and PARP and low &#101xpression of Ki67 and CD31 immunomarkers. In summary, we demonstrate the development of a robust polypeptide-based intracellular nanovehicle for synergistic delivery of DOX/QUR in cancer chemotherapy.
Web of Science Categories	Engineering, Biomedical; Materials Science, Biomaterials
Funding
Language

리스트

전체 Excluded 기타

	Scalable 3-D Carbon Nitride Sponge as an Efficient Metal-Free Bifunctional Oxygen Electrocatalyst for Rechargeable Zn-Air Batteries Author(s) : Shinde, Sambhaji; Lee, Chi-Ho; Sami, Abdul; Kim, Dong-Hyung; Lee, Sang... Source : ACS NANO 2017, 11, 1, 347-357 Time Cited : excluded
	Scalable 3-D Carbon Nitride Sponge as an Efficient Metal-Free Bifunctional Oxygen Electrocatalyst for Rechargeable Zn-Air Batteries Author(s) : Shinde, Sambhaji; Lee, Chi-Ho; Sami, Abdul; Kim, Dong-Hyung; Lee, Sang... Source : ACS NANO 2017, 11, 1, 347-357 Time Cited : excluded
	[Excluded] Estimation of gamma-rays, and fast and the thermal neutrons attenuation characteristics for bismuth tellurite and bismuth boro-tellurite glass systems Author(s) : Lakshminarayana, G; Kebaili, I; Dong, MG; Al-Buriahi, MS; Dahshan, A; ... Source : JOURNAL OF MATERIALS SCIENCE J Mater Sci (2020) 55:5750–5771 Time Cited : Excluded
	[Excluded] Estimation of gamma-rays, and fast and the thermal neutrons attenuation characteristics for bismuth tellurite and bismuth boro-tellurite glass systems Author(s) : Lakshminarayana, G; Kebaili, I; Dong, MG; Al-Buriahi, MS; Dahshan, A; ... Source : JOURNAL OF MATERIALS SCIENCE J Mater Sci (2020) 55:5750–5771 Time Cited : Excluded
	[Excluded]A Real-Time Demand-Response Algorithm for Smart Grids: A Stackelberg Game Approach Author(s) : Yu, M; Hong, SH Source : IEEE TRANSACTIONS ON SMART GRID 2016, 7, 879-888 Time Cited : Excluded
	[Excluded]A Dynamic pricing demand response algorithm for smart grid: Reinforcement learning approach Author(s) : Lu, RZ; Hong, SH; Zhang, XF Source : APPLIED ENERGY 2018,15, 220-230 Time Cited : Excluded
	[Excluded]Incentive-based demand response for smart grid with reinforcement learning and deep neural network Author(s) : Lu, Renzhi; Hong, Hong, Seung Ho; Source : APPLIED ENERGY 2019, 236, 937-949 Time Cited : Excluded
	[Excluded] An Incentive-Based Demand Response (DR) Model Considering Composited DR Resources Author(s) : Yu, Mengmeng; Hong, Seung Ho; Ding, Yuemin; Ye, Xun Source : IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS 2019, 66, 1488-1498 Time Cited : Excluded
	[Excluded] Combined effect of El Nino-Southern Oscillation and Pacific Decadal Oscillation on the East Asian winter monsoon Author(s) : Kim, Ji-Won; Yeh, Sang-Wook; Chang, Eun-Chul Source : CLIMATE DYNAMICS 2014, 42, 3-4, 957-971 Time Cited : Excluded
	[Excluded] Novel visible light active graphitic C3N4-TiO2 composite photocatalyst: Synergistic synthesis, growth Author(s) : Sridharan, Kishore; Jang, Eunyong; Park, Tae Joo Source : APPLIED CATALYSIS B-ENVIRONMENTAL 2013, 142, 718-728 Time Cited : Excluded
	[Excluded] Microalgae - A promising tool for heavy metal remediation Author(s) : Kumar, K. Suresh; Shin, Kyung-Hoon Source : ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2015, 113, 329-352 Time Cited : Excluded
	[Excluded] Effect of supplementary cementitious materials on reduction of CO2 emissions from concrete Author(s) : Yang, Keun-Hyeok; Jung, Yeon-Back; Cho, Myung-Sug; Tae, Sung-Ho Source : JOURNAL OF CLEANER PRODUCTION 2015, 103, 774-783 Time Cited : Excluded
	[Excluded] Engineering of cell microenvironment-responsive polypeptide nanovehicle co-encapsulating a synergistic combination of small molecules for effective chemotherapy in solid tumors Author(s) : Ramasamy, Thiruganesh; Ruttala, Hima Bindu; Chitrapriya, Nataraj; Poud... Source : ACTA BIOMATERIALIA 2017, 48, 131-143 Time Cited : Excluded
	[Excluded] Ag/Au/Polypyrrole Core-shell Nanowire Network for Transparent, Stretchable and Flexible Supercapacitor in Wearable Energy Devices Author(s) : Moon, Hyunjin; Lee, Habeom; Kwon, Jinhyeong; Suh, Young Duk; Kim, Dong... Source : SCIENTIFIC REPORTS 2017, 7, 41981 Time Cited : Excluded
	[Excluded] Emission of bisphenol analogues including bisphenol A and bisphenol F from wastewater treatment plan Author(s) : Lee, Sunggyu; Liao, Chunyang; Song, Geum-Ju; Ra, Kongtae; Kannan, Kuru... Source : CHEMOSPHERE 2015, 119, 1000-1006 Time Cited : Excluded

맨앞으로

앞으로

1 /

맨뒤로